Enhanced low dose rate sensitivity (ELDRS) and reduced low dose rate sensitivity (RLDRS) in bipolar devices

Hydrogen Contamination and Its Correlation with Enhanced Low-Dose-Rate Sensitivity

TrueBeam Low Dose Rate Investigation for Pulsed Reduced Dose Rate IMRT

The capability of the TrueBeam treatment system to deliver step and shoot IMRT plans at low dose rates was evaluated. Beam characteristics during low dose rates (5 to 100 MU/min) were evaluated for consistency using a planar ion chamber array. MU constancy, linearity, and beam profile symmetry were all found to be equivalent within 0.5%. The response of the Scandi Dos Delta 4 system was also ev...

Modification of Source Strength in Low-Dose-Rate Lung Brachytherapy with 125I and 103Pd seeds

Background: A new treatment approach for most patients who have undergone early stage non-small-cell lung carcinoma (NSCLC), is wedge resection plus permanent implant brachytherapy. However, the specification of dose to medium at low energies especially in heterogeneous lung is unclear yet.Objective: The present study aims to modify source strength for different configurations of 125I and 103...

Low-dose-rate or high-dose-rate brachytherapy in treatment of prostate cancer – between options

PURPOSE Permanent low-dose-rate (LDR-BT) and temporary high-dose-rate (HDR-BT) brachytherapy are competitive techniques for clinically localized prostate radiotherapy. Although a randomized trial will likely never to be conducted comparing these two forms of brachytherapy, a comparative analysis proves useful in understanding some of their intrinsic differences, several of which could be exploi...

Scientific Risk Estimation on Health Effects of Low Dose and Low Dose-Rate Radiation - An Overview

Estimation of the scientific risks of high dose radiation has been successfully quantified by many studies using several different approaches. However, the risk for low and low dose-rate radiation is obscure because of a lack of evidence. This risk is currently estimated by extrapolating the radiation response at high doses into low dose ranges for practical purposes. Recent challenges to exami...